Abstract
The 2020 edition of the Guidance for the Initial Clinical Practice of Pediatric Noninfectious Uveitis
was published for the first time in Japan. This was due to the lack of awareness of this rare diseases and the
lack of established treatment strategies in spite of intractable conditions. Therefore, pediatric
rheumatologists and ophthalmologists worked together to standardize optimal treatment and management,
and to ensure strong collaboration between pediatricians and ophthalmologists.
Pediatric noninfectious uveitis has few subjective symptoms at onset, and it has already progressed
to some extent at the time of diagnosis, and there are many cases with complications. It may also appear as
one symptom of systemic disease or require systemic treatment, that is why collaboration is important. This
article reviews the current situation of pediatric non-infectious uveitis based on overseas and domestic
epidemiological studies and other literature reports, and explains the reason why 'guidance is necessary'. In
addition, we will explain the matters described in the manual and explain the essences and cautions on how
to use them.
It is hoped that the use of this guidance will lead to the widespread recognition of non-infectious
uveitis patients in children, the expansion of new diagnostic tools, and therapeutic drugs, and the early
diagnosis and improvement of prognosis.
