A case　of juvenile　idiopathic　arthritis　with　congenital　heart　disease　treated　with　Tocilizumab．

Abstract

　This　case　is　l4 years　old　girl　who　diagnosed　with　polyarticular juvenile　idiopathic　arthritis　at　the　age　of 10 years　old.　Rheumatoid　factor　and　anti-cyclic　citrullinated　peptide　antibody　is　positive．　She　has　a　congenital heart　disease　which　is　a　common　atrium，　atrioventricular　septal　defect，　absence　of　the　inferior　vena　cava，　and polysplenia　syndrome．　She　was　operated　for　two　ventricular　repair　and　mitral　valve　plasty　at　the　age　of　l　year old．　At　first、　we　started　to　use　the　medicine　of　PSL　and　MTX，　however　the　effect　is　limited　for　her．　So　we planned　use　of　biologics (Tocilizumab)．　It　is　unknown　the　side　effect　against　heart　damage　of　using Tocilizumab．　We　assessed　that　her　cardiac　function　was　normal．　Therefore　we　treated　her　with　Tocilizumab． Her　cardiac　function　remains　stable．　It　is　suggested　that　the　use　of　Tocilizuinab　is　safe　for　JIA　with　congenital heart　disease．