Abstract
This case is l4 years old girl who diagnosed with polyarticular juvenile idiopathic arthritis at the age of
10 years old. Rheumatoid factor and anti-cyclic citrullinated peptide antibody is positive． She has a congenital
heart disease which is a common atrium， atrioventricular septal defect， absence of the inferior vena cava， and
polysplenia syndrome． She was operated for two ventricular repair and mitral valve plasty at the age of l year
old． At first、 we started to use the medicine of PSL and MTX， however the effect is limited for her． So we
planned use of biologics (Tocilizumab)． It is unknown the side effect against heart damage of using
Tocilizumab． We assessed that her cardiac function was normal． Therefore we treated her with Tocilizumab．
Her cardiac function remains stable． It is suggested that the use of Tocilizuinab is safe for JIA with congenital
heart disease．
