PREPARATION OF SILOXANE-CONTAINING VATERITE ⁄ POLY (LACTIC ACID) HYBRID BEADS BY ELECTROSPRAYING AND HA-COATING ON THEIR SURFACES

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Bead–shaped siloxane–containing vaterite (SiV) ⁄ poly (L–lactic acid) (PLLA) hybrid beads with ca. 40 – 130 μm in diameter were prepared by an electrospraying method. The beads included pores of ∼1 μm in diameter. SiV particles were embedded in the PLLA matrix. The beads containing 20 wt% of SiV showed the releasabilities of Si⁴⁺ and Ca²⁺ ions in a dilute acetic acid solution of pH 4. To improve cytocompatibility, the beads were coated successfully with a hydroxyapatite layer by soaking in simulated body fluid (SBF).