抄録
Porous hydroxyapatite (Ca10(PO4)6(OH)2; HA) coated with β-tricalcium phosphate (Ca3(PO4)2; TCP) was prepared by our unique method. The porous HA was soaked in diammonium hydrogen phosphate solution, and then the HA was sintered at 900°C for 3 hrs. β-TCP was formed on the surface of HA. It was possible to control the content of surface-formed β-TCP arbitrary by varying the concentration of the solution. The obtained HA coated with 33wt% β-TCP (33TCP) had about 60% open porosity with the pore size from 150 to 400 μm. The average compressive strength of 33TCP was 17.5 MPa. Surface coated HA with β-TCP deprived of the brittleness in handling. From the results of implantation into the femoral condyles of adult rabbits, this porous material showed good bone formation inner and around itself.