Study on spectroscopy-tomography of single-cell

Abstract

Currently, we study about spectroscopy-tomography of living single-cells which diameter is about 10 μm to assist the quantitative diagnosis of early cancer. By this method, we can obtain a 3-dimensional distribution of the cell components to a high spatial resolution. This technology is composed of two elemental technologies, a high spatial resolution spectrometry and a precise single cell rotating method. In this paper, we mention proximal two-beam optical tweezers as the precise rotating method. In this method, we can control the rotational velocity of microsphere regardless of refractive index distribution by non-contact operation. In this report, we experimented in rotation of a single cell and discuss rotation direction and rotation torque.