First Screening of Circulating Tumor Cells in Blood by Dimensional Difference

Abstract

Circulating tumor cells (CTCs) are tumor cells circulating in blood vessels, and several studies were performed on detection of CTCs. However, the number of CTCs are quite small compared to usual blood cells and the detection is difficult. It is also known that CTCs tend to be larger than usual blood cells. In this study, using the size difference, we attempted to enrich CTCs from blood by lateral displacement method with micro post structure. Tumor cells were dispersed in mouse blood, and the selection of tumor cells was demonstrated