抄録
In oriental medicine the conception of "oketsu" is known widely. This conception means stagnation of blood flow. Some herb medicines, which eliminate "oketsu" syndrome, are known as "ku-oketsu-zai". We attempt to study the effects of "ku-oketsu-zai" on the blood fluidity of rats by MC-FAN (micro channel array flow analyzer). Repeated oral administration of tokishakuyakusan or kangenkaryu as "ku-oketsu-zai" once a day for 1 week accelerated the blood fluidity of rats but single administration did not. It was experimentally demonstrated that "ku-oketsu-zai" actually accelerated the blood fluidity of rats. We are now studying whether "ku-oketsu-zai" may restore the reduction of blood fluidity by some stressors. [Jpn J Physiol 54 Suppl:S115 (2004)]