抄録
We estimated the regional temperature of the human brain in normal resting adult volunteers using 1H magnetic resonance spectroscopy (1H-MRS) at 3T, and compared our data with the results reported previously. Among 36 volunteers (19–65 years old), values of the temperature at deep white matter near the left cingulate gyrus and frontal lobe in 18 males were 37.4±0.4 (mean±SD) and 37.0±0.6°C (significantly different, paired t-test, P<0.05), and those in 18 females were 37.4±0.4 and 37.4±0.6°C (not significant). The temperature at the frontal lobe in the males was lower than that in the females (P<0.05). Moreover, the temperature at the deep white matter in the males, but not in the females, correlated with tympanic temperature (r=0.809, P<0.001). The measured values of the regional brain temperature were almost all consistent with the data reported previously, but some, such as the difference in regional brain temperature between males and females, or the correlation between the brain temperature and the tympanic temperature in males, are different from the results in previous reports. Our comparative study appears to indicate that factors affecting temperature should be taken into account to determine the regional brain temperature in detail. [Jpn J Physiol 54 Suppl:S234 (2004)]
