抄録
Two serum SH groups exist: nothing is bound to free-SH (F-SH), while compounds such as cysteine or glutathione bid via S-S bonds to bound-SH (B-SH). Total SH (T-SH) represents the sum of F-SH and B-SH. We have previously reported that hemodialysis, aerobic exercise and hyperoxia increase F-SH levels, while anaerobic exercise decreases F-SH levels. However, since methods for measuring B-SH levels have not been available, T-SH and the kinetics of serum SH have not been possible to determine. With improvements in SH group assays, B-SH levels can now be quantified. Using the new assay, the kinetics of F-SH and B-SH were ascertained before and after hemodialysis, following aerobic exercise, following anaerobic exercise and under hyperoxic conditions. The results are discussed herein. [Jpn J Physiol 55 Suppl:S230 (2005)]
