抄録
We have previously demonstrated that rhythmic exercises such as Zen abdominal breathing, gum-chewing, hula dancing and so on caused an increased 5-HT level in adult human. In this study, we evaluated urinary 5-HT level of pre-school children before and after the rhythmic exercise program (REP) including zigzag run, jumping rope, vaulting box, climbing bar, doing horizontal bar and overhead ladder etc. The subjects were 11 junior (4-5 years old) and 8 senior (5-6 years old) pre-school children. We found that the mean 5-HT level in senior pre-school children was higher than that in junior pre-school children before REP. This high 5-HT level in senior children may be due to a neuronal developmental of serotonergic system. REP induced an increase in 5-HT level in 6 of 11 junior children and 6 of 8 senior children. Although the rest children showed the decreased 5-HT level after REP, three of 5 junior children and one of 2 senior children had markedly high 5-HT level before REP. The decreased 5-HT level after REP may be derived from an exercise-induced fatigue. [J Physiol Sci. 2007;57 Suppl:S177]