抄録
Physical exercise is used for improvement of hypertension and hyperglycemia, and for the rehabilitation of ischemic heart disease. However the effect of physical exercise on the blood fluidity is not well known. In the present study, we studied the effect of exercise at different intensity on the blood fluidity using micro channel array flow analyzer (MC-FAN) method. MC-FAN mimics the blood flow in the capillary vessel. Physical exercise at HRmax60% by bicycle ergometer for 30 minutes did not affect the blood fluidity in human volunteer. Water intake immediately after the physical exercise improved blood fluidity but the effect retuned to the control level 30 minute after exercise. However, by Wingate anaerobic test for 30 seconds, blood fluidity decreased 5 and 30 minutes after exercise in using heparin as an anticoagulant but not in using EDTA. EDTA blocks both blood coagulation and platelet agglutination. On the other hand, heparin only blocks blood coagulation and does not affect to the platelet agglutination. Therefore physical exercise at high intensity may impair the blood fluidity through platelet agglutination mechanism. These results indicate that high intense exercise may unsuitable for rehabilitation and water intake is effective for improvement of blood fluidity. [J Physiol Sci. 2007;57 Suppl:S216]
