品質工学
Online ISSN : 2189-9320
Print ISSN : 2189-633X
ISSN-L : 2189-633X
開発と研究
蒼朮の化学成分に基づく地理的変異の鑑別(1)
-マハラノビスの距離による解析-
中井 洋一郎矢野 耕也榊原 巌寺林 進油田 正樹竹田 秀一
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2005 年 13 巻 4 号 p. 56-65

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The Atractylodes lancea rhizome used as an ingredient of Kampo medicines is a natural medicine derived fom plants in the aster family (Compositae) found in China. Regional differences in quality are observed. To produce Kampo medicines with consistent quality, a componential analysis of the Atractylodes lancea rhizome material was carried out by two types of chromatography, and the MT system was applied to the included quantities often components having pharmacological effects. A unit space was constructed, referenced to specimens from regions described in classical literature as producing superior quality. The distances between specimens from eighteen production sites in China were determined by the inverse matrix method. Components were selected for each region and a classification was made from differences in the contribution ratio of the signal-to-noise ratio (S/N) and sensitivity (S) of the ten components. As a result, it was found that the regions could be roughly classified into four north-south-east-west patterns centered on the production sites used in the unit space. The results obtained by the MT system also enabled the results of the componential analysis to be interpreted more precisely.

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© 2005 一般社団法人 品質工学会
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