Abstract
Liquid chromatographic/(LC) analysis is an effective instrument for pharmaceutical analysisand pharmaceutical science. Various methods have been utilized in attempts to optimize LC analytical conditions. ln order to obtain a high degree of separation, the optimum conditions were determined by the use of dynamic S/N ratio as an index for the evaluation of the separation process. An L18 orthogonal array was used in this experiment. lt was demonstrated that S/N ratio was an appropriate scale to indicate the separation of some peaks in a LC. Also, the appropriate types of S/N ratio to show the degree of separation in a LC was discussed.
