Activity Standardization of 177Lu with 4πβ–γ Coincidence Counting Method

Yasushi Sato; Rio Furukawa; Chihiro Shimodan; Ryan Smith; Hideki Harano

doi:10.3769/radioisotopes.740305

Articles

Activity Standardization of ¹⁷⁷Lu with 4πβ–γ Coincidence Counting Method

Yasushi Sato , Rio Furukawa, Chihiro Shimodan, Ryan Smith, Hideki Harano

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Keywords: Lutetium-177, standardization, 4πβ–γ coincidence counting, theranostics, prostate cancer

JOURNAL OPEN ACCESS

2025 Volume 74 Issue 3 Pages 301-307

DOI https://doi.org/10.3769/radioisotopes.740305

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Abstract

Radiopharmaceuticals containing ¹⁷⁷Lu are used in nuclear medicine therapy. The National Metrology Institute of Japan has therefore standardized the activity of ¹⁷⁷Lu by 4πβ–γ coincidence counting using gamma-rays with energies of 113 and 208 keV. The traceability of activity measurements for ¹⁷⁷Lu in Japan is ensured by this standardization.

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