Synthesis of Optically Active Cyphenothrin-¹⁴C

—¹⁴C-Labelling at the vinyl carbon—

Abstract

Optically active cyphenothrins, α-cyano-3 phenoxybenzyl (1R) -cis- and (1R) -trans-chrysan-themates, were labelled with ¹⁴C at the vinyl position for use in metabolic studies. The key intermediates, (1R) -cis- and (1R) -trans-chrysanthemic- (propenyl-2-¹⁴C) acids (9a and 9b), were synthesized stereospecifically by applying the Wittig reaction of ¹⁴C-labelled phosphorane (6) with optically active formyl esters (7a and 7b) .