RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
Late Effect of Radiation on Blood Clearance of 99mTc Sodium Pertechnetate
Tarek ELNIMR
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Keywords: technetium-99m-sodium pertechnetate, blood clearance, gamma radiation, hepatic dysfunction, rat
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1992 Volume 41 Issue 5 Pages 253-256

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Abstract
The late effect of gamma radiation on blood clearance of 99mTc-sodium Pertechnetate (99mTc-SP) in rats was examined.
The disappearance rate of99mTc-SP from blood decreased with the increase in dose of ionizing radiation. Changes of the blood clearance of99mTc-SP after irradiation treatment in rats may be influenced by the disorder in the hepatocytes rather than in the bile ductule cells. The blood clearance test of99mTc-SP in rats showed a sensitive reaction for the acute hepatic dysfunction induced by gamma radiation.
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© Japan Radioisotope Association
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