We evaluated the safety and clinical usefulness of cerebral and myocardial blood flow measurement by means of positron emission tomography (PET) with automated synthesis system of [15O] H2O (ARIS-02, JSW) in 62 patients with either brain disorder (n=31) or cardiac disease (n=31) . In all 62 patients, no side effects were detected after administering [15O] H2Ointravenously. The quality of the PET images were“fairly good”or“good”in all the cases. When compared with other imaging modalities such as computed tomography, this method provided physiological and functional information on the brain and cardiac diseases. We concluded that the PET measurement of cerebral and myocardial blood flow using automated synthesis system of [15O] H2Ois clinically useful.
