抄録
As far as PAS positivity in erythroblasts is concerend, it has been generally found to be negative. In 1960, however, Quaglino reported that erythroblast in some hematological disorder show PAS positive and pointed out the diagnostic evaluation for di Guglielmo syndrome. This investigation purposed to clear PAS positivity in erythroblast on different pathological condition and its clinical evaluation.
PAS reactions which obtained different method carried out on the bone marrow smears of 108 cases with various disease including a case of normal adult and human fetal erythroblast.
For frequency of PAS positive erythroblasts, 100 erythroblasts of each specimen were observed and percent positivity were counted. In all specimens, the percent positivity showed from 4 to 90% and some conclusions were obtained as follows;
1) It seemed that PAS reactive erythroblasts have no correlation with the erythroid proliferaiton and occur in all specimens.
2) As with PAS positive lymphocytes, the percent positivity of PAS positive erythroblasts revealed a different value depend on a method (various temperature and pH for reaction) of PAS reaction.
3) Although the percent positivity of PAS positive erythroblast showed high frequence on erythroleukemia, acute myelocytic leukemia and suspected di Guglielmo syndrome, percent positivity of PAS positive erythroblast may not be valuable index for diagnosis of special disease such as malignant erythroid disturbance.
