臨床研究
放射性鉄を用いたTIBC測定法の臨床的検討
1973 年 14 巻 7 号 p. 795-799
詳細
1973 年 14 巻 7 号 p. 795-799
Determination of Total Iron Binding Capacity (TIBC) using Res-O-Mat Fe kit (TIBC) offered by Daiichi Radioisotope Labs., Ltd. was investigated.
Procedure of this kit was easier than colorimetry or immunological method and the error in assay due to iron contamination of instruments or reagents and deproteinization as in colorimetry was hard to occur in this kit method.
The reproducibility of assay value of the same serum was good (coefficient of variation was 5%) and no effect of keeping in a frozen state could be observed.
The corelation between TIBC value by this kit and the value of SI+UIBC by the other method was good (γ=0.89) and the value by this kit was slightly the lower.
With normal subjects, TIBC value and transferrin was corelated well, but with various diseases, both were not so well corelated. In iron deficiency anemia, anemia of pregnancy, leukemia and aplastic anemia, TIBC value was higher than the value of SI+UIBC.
Though further investigation will be needed in the future, this kit method is found to be useful in clinical application, because the exact TIBC value is obtained easily in a short time by anyone.
