A case, 7-year-old girl, of Hb M Hyde Park was presented. The diagnosis was made on data gained by ESR (electron spin resonance) determining method. The half time of her red cell life span was estimated by 51Cr method and disclosed to be 15 days. The bone marrow showed marked erythroid hyperplasia, although no abnormalities were found on the myeloid series. The amount of the D-2, 3-diphosphoglycerate in her red cell was within normal limits.
In this report, the authors mentioned the efficacy of ESR determining method for diagnosing the Hb M disease. The accuracy and simplicity are the best point of ESR method.
