1973 年 14 巻 Suppl. 号 p. S1393-S1399
One of five patients in a family with hemophilia A developed an inhibitor to factor VIII, being of IgG-antibody in nature. And it has been demonstrated that this inhibitor might have an inhibitory effect on platelet aggregation observed by recalcification method. Patientd eveloped an inhibitor has been successfully managed with Reptilase treatment.