抄録
The case reports of autoimmune cold agglutinin hemolytic anemia associated with Mycoplasma pneumonia have still been uncommon.
A55-year-old female, who had been well for 2 years after recovery from aplastic anemia, was admitted on April 10, 1975, with the chief complaints of fever and cough. On admission, there were clinical and radiological signs of pneumonia in the left lung. The ESR was 164 mm/hr and her hemoglobin level being previously 13.0 gm/100 ml fell down to 6.5 gm/100 ml. The reticulocyte count was 13.8%, the indirect serum bilirubin 1.3 mg/100 ml and the serum haptoglobin undetectable. The direct Coombs' test was positive and antibodies on the erythrocytes were found to be IgM and C3. The titer of serum cold agglutinin was elevated to 1 in 32768 on the twelfth day of admission, and the Mycoplasma pneumonia CF titer rose from 1 in 8 to 1 in 128 within 10 days. From these data the diagnosis of autoimmune cold agglutinin hemolytic anemia associated with Mycoplasma pneumonia was made. On discharge 12 weeks after admission, the hemoglobin level was 11.7 gm/100 ml, the reticulocytes 1.3%, the direct Coombs' test negative, and the cold agglutinin titer 1 in 1024. The chest X-ray showed no abnormalities and the Mycoplasma pneumonia CF titer was 1 in 64.
