1979 年 20 巻 3 号 p. 292-300
A case of Immunoblastic Lymphadenopathy (IBL) with repeated interstitial pneumonitis was reported.
In this case, at the early clinical stage lymph node speciemen showed only reactive lymphadenitis but later it changed to the typical IBL from pathological findings. The remission and relapse of the interstitial pneumonitis which may be due to the infiltration of immunoblasts and lymphadenopathy were repeated without any treatment. From the results of the immunological research of this case, we concluded that the immunological abnormality of IBL might be observed in the quantitative and qualitative aspects.
It may be important for the treatment of IBL to correct this immunological abnormality, since this abnormality is subject to be influenced by various cytotoxic agents and develop to immunoblastic sarcoma.