抄録
Review of literatures on 32 cases of primary thrombocythemia including the present authors' case was made.
1) Sex incidence of the disease was 14 and 18 in male and female, respectively.
2) As to age incidence, it was found that more than half cases reviewed was over 60 years of age.
3) Main symptoms of the disease were roughly divided into two: (1) symptoms due to bleeding of various origin (68.7%) and (2) symptoms probably attributable to changes of vascular obliteration (50%).
Cases with swelling of the liver, spleen or lymph nodes were found in 41.9%, 46.8% or 9%, respectively.
4) Hematologically, 90% of the cases had an increased peripheral platelet count of more than 100×104/μL, but there was no correlation observed between the peripheral platelet count and the bone marrow megakaryocyte or nucleated cell count. Furthermore, no definite tendency was observed in the results of coagulation tests.
5) Finally, while chemotherapy with busulfan has been most widely adopted in treating primary thrombocythemia, it should be remembered that 6 cases of the disease has followed a relatively good course irrespective of no special therapy given.
