Experimental Studies of the Platelet Aggregation by The Filtragometer
—The Platelet Aggregation in Myocardial Infarction—
1980 Volume 21 Issue 1 Pages 39-45
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1980 Volume 21 Issue 1 Pages 39-45
We have investigated platelet aggregation in myocardial infarction (MI) by the Filtragometer and obtained the following results:
1) The average aggregation time (TA) in patients with MI was 110.9±89.9 seconds, and this was shorter than that of control subjects which was 264.8±53.9 seconds. These patients were classified into two groups by the change of TA in the further clinical course. In the first group, TA became longer up to the normal range, and in the second group, it was restored to reference range at 3∼4 day after MI episode and became shorter than the normal.
2) The mean of the platelet disaggregation time (TD) in MI subjects, which was 60.5 seconds, was longer than that of the control subjects (47.0 seconds).
3) The TA was not correlated with plasma factors, such as fibrinogen, lipids and sugar, and b/2 time in the Aggregometer.
