1980 年 21 巻 11 号 p. 1674-1682
The surface makers and functions of human lymphocytes have been widely studied in various immunological diseases. Along with the progress in these investigations, a better classification of lymphoproliferative disoders has been also attempted.
Lutzner et al. suggested that the Sézary syndrome, mycosis fungoides, and related disoders were grouped together as “Cutaneous T-cell Lymphoma”.
Takatsuki et al. recently proposed the concept of “Adult T-cell Leukemia” based on their observations on patients natives of south Kyushu in Japan. They thought that “Adult T-cell Leukemia” was different from the classical Sézary syndrome.
We observed 16 similar cases including 4 probable cases, which were identical to, resemble with, or distinct from the Sézary syndrome. But it was very difficult to separate them from each other by a definite line. We thought that all these cases were essentially identical to Sézary syndrome.
It is suggested that Sézary syndrome, mycosis fungoides, adult T-cell leukemia and T-CLL or some of T-lymphomas with abnormal cells containing bizarre nucleus are the same disease.