抄録
Nine cases of bone marrow transplantation have been performed since 1975 for the treatment on 6 cases of acute leukemia (ALL, 4. AML, 1. AMoL, 1.) and on each of aplastic anemia, chronic myelogenous leukemia and malignant lymphoma.
In earlier 6 cases no marrow engraftment was established, but in a case of aplastic anemia the complete hematological recovery of the host type marrow was noted on 60 days after the bone marrow transplantation and has persisted for 31 months.
In recent 3 cases marrow engraftment was confirmed by the analysis of chromosomes, but all of patients were died by severe infections such as fungal, viral septicemia and pneumocystis carinii pneumonia. The longest survival dutation after engraftment was 106 days for acutelymphocytic leukemia. Only grade I of GVH reaction was found in two of these 3 cases.
