3. 貯蔵鉄と血清フェリチン

抄録

Serum ferritin concentration as a measurement of storage iron was evaluated by the two site immunoradiometric assay technique. Normal value of serum ferritin in male and female was 144±75 and 40±22 ng/ml respectively. In the patients with iron deficiency anemia, serum ferritin value was less than normal (6.8±5.1 ng/ml, the same in male and female), and turned to normal after iron supplement therapy. Serum ferritin concentration in the population was measured near Fukushima city. The results showed 25% of pre-latent iron deficiency (low ferritin value with normal serum iron, TIBC and hematocrit) in adult female. In the iron overload states, there was good relationship between serum ferritin and storage iron. There were also good correlations between serum ferritin, total liver iron, hemosiderin and ferritin content in the experimental iron-overloaded rats. In conclusions, it was discussed serum ferritin concentration was good indicator of storage iron measurement.