Abstract
Serum ferritin were measured by SPAC FERRITIN KIT (immunoradiometrical assay) on 20 cases with various type of hemolytic anemia, 6 PS, 2 PNH and 12 Coombs positive. And the results are as in followed:
Serum ferritin level is elevated in generally with relatively moderate degree (420.0±410.2 ng/ml, normal level are 79.0±30.4 and 26.7±9.9 female) among various blood diseases associated with hyperferritinemia. But in there, big differences were seen between case by case and these individual difference looks like most important problems to be disolved.
The statistical data induced from references between serum ferrin and RBC, Hb, Rc, Serum iron, Iron saturation rate of transferrin, PID, PIT, RCIUR, Red cell ferritin and also therapeutic course suggests that elevated serum ferritin level in hemolytic anemia are very concerned to next two main fundamental mechanism, (1)…the total iron stores of individual patient and (2)…the red cell ferritin destroyed continously.
