Abstract
Fiftyeight Hodgkin's diseases in National Cancer Center Hospital were classified into the following three types.
One is “localized type (L-type)” in which lymph node involvement localizes in the initial site for five months or more. The other is “generalized type (G-type)” in which lymph node involvement extends beyond the initial site within five months. The third of “other type (O-type)” includes following cases which can not be classified into both L-type and G-type. These 58 cases include 25 L-type, 20 O-type and 13 G-type cases.
Prognosis is better in L-type than G-type and median survival time in the former is 8 yrs. 11 mos. but only 11 mos. in the latter. That of O-type is relatively well and 50% survival time is 6 yrs. 8 mos. L-type includes highly good prognostic factors, for example, younger age, stage I & II and LP & NS. On the other hand, G-type includes highly bad prognostic factors, for example, older age, stage III & IV and MC & LD.
In L-type, cervical lymph nodes were involved initially 96% but in G-type, axillar and/or inguinal lymph nodes were involved initially 60%.
Duration from onset to diagnosis is longer in L-type than G-type and mean interval time is 18.1 mos. and 2.2 mos., respectively.
This classification is available for clinicians to presume prognosis of Hodgkin's disease besides the problem of one third in our cases belonging to O-type.
