抄録
A child of Acte Lymphocytic Leukemia with seizures and mental retardation which developed gradually during and after maintenance chemotherapy is reported.
This child received only 1940 skull irradiation and five doses of intrathecal methotrexate and never had intravenous nor intrathecal methotrexate during maintenance chemotherapy.
The etiology of neurological impairment in this case was discussed with special reference to leukoencephalopathy. A need for national wide research on grave neurological sequalae in chemoradiotherapy of childhood ALL was stressed.
