1983 年 24 巻 9 号 p. 1271-1276
Concerning malignant lymphoma and ATL of in-patients at our hospital since 1981, hematological as well as virological investigations were done.
1) In the non-Hodgkin lymphoma group, about half of the cases showed T-cell type, which is similar to that seen in other regions of Kyushu. Diffuse lymphoma was most prevalent, affecting about 87% of the patients, and more than 85% showed progressive status more than stage III.
2) There were 13 cases of ATL. Conspicuous increases in serum LDH value and peripheral blood leukocytes were observed. In 7 cases, hypercalcemia was recognized. It was resistant to treatment, and the prognosis was unfavorable.
3) The positivity rate of anti-ATLA antibodies in serum was 100% in ATL and was 50% in T cell type lymphoma, but the rate was lower in B-cell type and null-cell type lymphoma.
4) In the detection of anti-ATLA antibodies in 13,329 healthy adults inhabiting Kumamoto Prefecture, the rate of positivity increased with aging, and was higher in females than in males. As for geographical distribution, it was higher in a certain area but was found to be widely distributed throughout the prefecture.