1984 年 25 巻 9 号 p. 1442-1445
A 70 years old woman was admitted to our hospital with the complaints of bleeding tendency, exertional palpitation, and a skull tumor on May 16, 1983. The diagnosis of lymphocytic leukemia complicated with disseminated intravascular coagulation was made from her hematological and coagulation studies. Although she recieved the therapy of heparin, prednisolone and vincristine, she died of the massive gastrointestinal bleeding.
The surface marker studies of her leukemic cells using immunological techniques revealed B-ALL phenotype. This case was definable as type L2 according to FAB classification of acute leukemia, almost all the cases of tumor forming leukemia were included in type L2 and B-ALL were included in L3.
These results suggest that there may be the interesting relationship between the immunological defined surface markers and tumor forming leukemia.