A case of acute myelocytic leukemia (AML) complicated with intracerebral leukemic tumor is reported.
A 45 year-old housewife was found to be anemic during medical examination in October, 1981. She was treated for anemia from December 2. Because of continuing fever and general malaise, she was transferred to the Toyama Medical and Pharmaceutical University Hospital on December 21. She was diagnosed as AML (FAB classification M2) by hematological examination, and the DCMP two-step therapy was immediately started. Despite good response to the therapy, she complained of vertigo, nausea, vomiting and cerebellar signs early in August, 1982. Brain computed tomographic examination revealed a high density area near the cerebellar vermis, and diagnosis of meningioma was made. Because her symptoms became worse, she was operated on August 24. The resected tumor had brown color and smooth surface. The size of tumor was 4.5×3.0×2.5 cm and the weight was about 10 g. Histologically, the tumor consisted of a mass of leukemic cells combined with proliferated reticulin fibers. Histological diagnosis was leukemic tumor. One and half month after the operation she died of pulmonary hemorrhage.
