Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
A Case of Chronic Myelogenous Leukemia of Juvenile Type with Special Regard to Hemopoietic Stem Cells
Keiichi ISOYAMAKohichiro YAMADAAkira ISHIKAWA
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Keywords: JCML, BFU-E, CFU-E, CFU-C
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1986 Volume 27 Issue 2 Pages 191-196

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Abstract
Studies on the hemopoietic colonies (CFU-C, BFU-E and CFU-E) were performed with bone marrow cells and peripheral blood in a patient with chronic myelogenous leukemia of the juvenile type (J-CML).
In the bone marrow, hemopoietic colonies of earch type were grown within a normal limit as compared with healthy subjects. Before treatment, a remarkable number of CFU-C was seen.
In a serial study, the appearance of these progenitor cells in peripheral blood of a patient seemed to be related to viral infection and chemotherapy.
A positive relationship was observed between BFU-E and reticulocyte count.
A large number of colony forming cells in the stage of DNA synthesis were observed in this case as seen those of adult type of CML.
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© 1986 The Japanese Society of Clinical Hematology
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