1986 年 27 巻 4 号 p. 560-564
A 27 year-old male with acute lymphoblastic leukemia who was treated with high-dose cyclophosphamide (120 mg/kg) and total body irradiation (1,000 rad), followed by bone marrow transplantation from his HLA-identical sister in the first relapse. Although the posttransplant clinical course was complicated with grade II acute graft-vs-host disease (GVHD), interstitial pneumonia and an extensive form of chronic GVHD, all of these complications were successfully treated. The patient is now alive and well in unmaintaned remission over 7 years after transplantation. A leukemia-free long-term survival observed in this patient suggests a probable cure of leukemia. Factors influencing on long-term survival are discussed.