It is generally accepted that few women of acute leukemia become pregnant. This paper describes our recent experience of a case of leukemia, a 29-year-old woman who had a stillborn baby in the 10th month of pregnancy and an artificial abortion at nine months later.
1st admission: She was admitted to our hospital in April, 1964 in the 7th month of pregnancy, because of severe anemia. Physical findings and laboratory examinations including peripheral blood and sternal puncture smear as well as tissue culture of bone marrow, showed that she was suffering from acute lymphocytic leukemia. Although her general condition was improved by an intensive treatment with prednisolone and blood transfusion, she gave a stillbirth due to abruptio placentae. Autopsy of the baby revealed no leukemia.
2nd admission: She was admitted in January, 1965, because of a certain degree of leukemic condition and pregnany. After antileukemic treatment, artificial abortion was successfully performed, Approximately one month later, fever, adenopathy and splenomegaly reappeared and in May, 1965, she was expired.
It is our impression that pregnancy exerts some ameliorating effect on the leukemic condition.