1968 年 9 巻 1 号 p. 13-21
From the investigation on the total 104 cases of variuos hematological diseases, the following results were obtaind.
The platelet productivity of megakaryocytes strikingly decreased in the cases of acute and chronic leukemia. However, the number of megakaryocytes in chronic leukemia remarkably increased contrary to the marked decrease of megakaryecytes in acute leukemia.
The definite correlation between the phase of acute leukemia in childhood and platelet productivity of megakaryocytes was obtained.
In the cases of ITP, platelet formation from megakaryocytes remarkably diminished in spite of the increase of their number. The cases of iron deficiency anemia, secondary anemia and hypoplastic anemia revealed no decrease of platelet production. The cases of Banti's syndrome indicated a slight depression of platelet formation.
In a case of megaloblastic anemia following the total gastretomy, platelet production from megakaryocytes decreased before treatment, and recovered after the injection of V. B12.