2008 年 52 巻 3 号 p. 151-154
Recent development involves practical and universal usage of microfabricated devices (microfluidic chip) for analysis of biological molecules. Agilent 2100 Bioanalyzer, launched in 1999, is a unique tool capable of handling nucleic acids, proteins and cells on one platform, and for obtaining accurate, reproducible and high-resolution analytical results. For example, RNA is the starting point for several applications, like RT-PCR and microarray, and knowing that the starting RNA is of sufficient quality is vital for success of these applications. Bioanalyzer not only acquires migration profiles of RNA samples, but also automatically assesses their integrity in an objective manner. And besides, it has so many benefits over conventional bioanalytical methods, the elimination of time consuming procedure and the reduction of the sample contamination. In this report, we show its basic feature and new applications for small RNA and highly sensitive analysis of proteins.