抄録
The change of mitochondria aspartate aminotransferase (mAST)/soluble AST (sAST) ratio was examined in 22 cases of acute myocardial infarction (AMI). The mAST/sAST was 0.408±0.189 at admission to a hospital (2.9±1.6h). The mAST/sAST decreased to normal value rapidly after peak and then increased again gradually. The decrease ratio of mAST/sAST per minute at early stage of 8 cases, who were succeeded to reperfusion, was 0.28±0.20, and that was significantly higher than of conventionally treated 7 cases and non-reperfused 7 cases (0.11±0.07). These results indicated that (1) mAST/sAST may be an excellent indicator for AMI in early stage. (2) The decrease ratio of mAST/sAST would predict whether reperfusion is successful or not at an earlier stage of AMI.
