可溶化量測定によるO/Wエマルジョンの最適乳化条件の予測
1977 年 11 巻 2 号 p. 32-42
詳細
1977 年 11 巻 2 号 p. 32-42
Studies on the effect of surfactant location on O/W emulsifiction, revealed a useful correlation between the maximum amount of aqueous phase that could be solubilized in the oil phase containing the emulsifier and the average droplet size of the emulsion subsequently formed.
It is suggested that this correlation may be applied to develop a tool which can minimize the need for a trial-and-error process in selecting the best surfactant combination for a given emulsion formulation. The proposed method would have an advantage over Griffin's “required HLB” concept as, unlike required HLB values, solubilization measurements are relatively simple and the results are reproducible. Furthermore, this method should be more reliable since it takes into account the effects of other additives in the oil and aqueous phase.
The correlation between solubilization and emulsification is believed to be related to the basic emulsification mechanism.
