若年女性の頭皮・毛包・毛幹相互の関連性について

抄録

This paper reports the relationships between various parameters obtained from measurements on scalp skin, hair follicle and hair shaft in young females (13-28 years old, n=37).
Parameters measured are; (1) sebum contents (2) surface temperature (3) water contents (4) stratum corneum cell area, as to scalp skn; (5) glucose-6-phosphate dehydrogenas (G6PDH) (6) transglutaminase (TGase), as to hair follicle enzyme activities; and (7) cross-sectioned area (8) cuticle scale edge pattern (9) tensile strength (10) limiting extension (11) frictional coefficient (12) amino acid composition (13) cystine contents (14) polar lipids contents (cholesterol sulphate and ceramides) (15) contents of trace elements (Mg, K, Ca, Fe, Cu, Zn), as to hair shaft. The effects of hair care customs and hair treatments on the chemical and physical properties of hair were also investigated.
As the results from statistical analysis of these various parameters, a positive correlation (p<0.001) between hair follicle G6PDH and cross-sectioned area of hair shaft, and a negative correlation (p<0.01) between G6PDH and cuticle scale edge pattern were elucidated. These facts suggest that G6PDH plays an important role in a formation of hair follicle size and structure as a reflection of mitotic activity. Another negative correlation (p<0.01) between frictional coefficient and TGase was detected, and this enzyme seemed to participate in the hardening of cuticular structures.
Relationship between parameters for scalp skin and physico-chemical properties of hair shaft was not clear.
Permanent waving of hair appeared to decrease cystine content, water content of hair tip, and to increase Mg and Ca contents. This implies the damaging of hair shaft caused by hair treatment.