Proceedings of the Annual Conference of the Institute of Systems, Control and Information Engineers
The 47th Annual Conference of the Institute of Systems, Control and Information Engineers
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Improvement of a Sedation Control System Under Intravenous Anesthesia
Yoshihito Sawaguchi, Eiko Furutani, Gotaro Shirakami, Mituhiko Araki, Kazuhiko Fukuda
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Keywords: intravenous anesthesia, propofol, model predictive control, BIS index, robust stability analysis, clinical application
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Pages 5040

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Abstract
In ambulatory surgery, anesthetic drug must be administerd at an appropriate rate to prevent side effects after discharge from hospital. In this study, we have been developing a sedation control system using a model predictive controller. Propofol is used as the intravenous anesthetic drug, and Bispectral Index (BIS) is used as the index of sedation in our system. In this paper, we improve the pharmacodynamic model used for estimation of the effect-site concentration of propofol. The effectiveness of the modified system is evaluated by clinical application.
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© 2003 The Institute of Systems, Control and Information Engineers
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