2025 年 11 巻 1 号 論文ID: cr.25-0146
INTRODUCTION: Colon leiomyosarcoma (CLMS) is an extremely rare neoplasm and the information regarding its clinical characteristics and specific treatment was still unclear.
CASE PRESENTATION: A 73-year-old female who had been diagnosed with transverse CLMS underwent laparoscopic surgery. The resected specimen showed that the tumor contained proliferation of spindle-shaped cells and arranged in fascicular pattern, which was immunohistochemically positive for smooth muscle actin and desmin. Moreover, the tumor bottom was not continuous with the muscularis propria and had a clear border in the submucosa layer. According to these findings, we finally diagnosed it as primary CLMS arising from the muscularis mucosa (MM). No recurrence was noted 24 months after surgery.
CONCLUSIONS: This literature demonstrates CLMS arising from MM and suggests that its pathological diagnosis is associated with disease prognosis.
