We describe 2 surgical cases with de novo cerebellar cavernous angioma (CA). The first was a 56-year-old woman who presented with symptoms of increased intracranial pressure and cerebellar signs. Neuro-imaging findings demonstrated a heterogeneous hemorrhagic mass lesion in the right cerebellum, which was totally resected. Retrospectively, no lesions were detected in T2-weighted (WI) magnetic resonance (MR) images obtained 3 years 4 months prior to the operation.
The second case was a 40-year-old woman with symptoms of increased intracranial pressure and cerebellar signs. She had undergone surgical treatment for cerebellar hemorrhaging in the vermis due to CA with asymptomatic coexistent venous angioma 7 years prior. Retrospectively, a small de novo lesion was seen in the left cerebellum on T2-WI MR images obtained 3 years before our examination. The lesion grew to a large heterogeneous hemorrhagic mass in the left cerebellum, which was resected surgically.
Both cases were compatible with CA histologically, and neither had a family history of CA or radiation therapy. We concluded that the de novo appearance, growth along with bleeding, indicated the etiology in these 2 symptomatic cases of cerebellar CA.
