133Xe inhalation rCBF measurements were performed twenty-one times on seven patients with“Moyamoya”disease, four of whom were studied both pre- and post-operatively. Furthermore six of them were also studied with CO2 response of rCBF. Because of its easiness to re-examine and non-invasiveness inhalation method is thought to be clinically useful, especially studying with CO2 response on the patients with the cerebrovascular disease. And our study showed firstly the impairment of physiological response to hypercapnea on the young patients with“Moyamoya”disease, which have been well investigated with other methods. Secondary we observed the increase in inhomogeneous distribution of the cortical blood flow in post-operative period on the patients who were surgically treated with the vascular reconstruction method.
