Regional cerebral hemodynamics on twelve cases with Moyamoya disease was investigated by intra-venous 133Xe injection method using“Valmet rCBF Analizer”Eight cases out of twelve were children and other four cases were adults. Although their initial symptoms were ischemic attacks, no or only slight neurological deficits were found at the cerebral blood flow studies.
In the adult group, hemispheric cerebral blood flow was within the normal range. While in the child group, it was higher than the adult group. The distribution of the regional cerebral blood flow was characteristic in both groups. Namely, regional cerebral blood flow in the frontal and temporal region was relatively lower than the parietal and occipital region. It seems to indicate the importance of blood supply from vertebro-basilar system in Moyamoya disease.
Cerebral blood flow changes by hyperventilation was investigated in order to solve the mechanism of“Rebuild up”on EEG. But there was no difference between the cases showing“Rebuild up”and no“Rebuild up”though the cerebral blood flow after hyperventilation was decreased in both groups.
