For the treatment of dural arteriovenous malformations, conjugated estrogens were infused continuously through a catheter, inserted into the external carotid artery. In nine of 11 cases (81.9%), therapeutic effects on the angiogram, such as total or partial disappearance of the nidus, were observed. As for adverse reactions, to the drug there was parotitis (7 of 11 cases), liver dysfunction (2 of 11), and gynecomastia (1 of 11). These symptoms were easily corrected by discontinuing or reducing of the estrogen dosage. There were no serious adverse reactions and recurrence was not observed. Therefore, this chemical embolization method using estrogen is an easy, safe and effective treatment for dural arteriovenous malformations.
