To examine the relationship between dysuria and cognitive function, we compared cognitive function test (D-CAT, letter fluency test, semantic fluency test, and logical memory test) performances, body fat percentage, BMI between the MD group (N = 112, 40-89 years old) and the Intact group (N = 102, 40-87 years old). Participants who did not reach UI but experienced dysuria assessed by Overactive Bladder Symptom Score (OABSS) were classified to the MD. As a result, D-CAT showed a significant group difference. This finding suggests a decline in the frontal lobe function for the MD group and it reconfirms the results of our previous study on UI (Hatta et al., 2011), which slows the decline of higher brain function. We discussed the importance of the training of the frontal cortex function from early stage of MD symptoms such as pollakiuria.
