Multi-Residue Determination of 110 Pesticides in Agricultural Products by GC/MS (SIM)

Abstract

A method is described for the multi-residue determination of pesticides in agricultural products. Residues are extracted from samples with acetonitrile, and coextractives are removed by gel permeation chromatography, followed by a clean-up step through Bond Elut PSA and a silica-gel column. Analysis is performed by GC/MS (SIM). The method was evaluated in 4 or 5 laboratories for 110 pesticides by fortifying rice, apple, orange, spinach, cabbage and potato at 0.2 μg/g (for 5 pesticides, 1 μg/g) of each pesticide. The method gave acceptable performance for analysis of 77 pesticides. The maximum detection limit in 9 laboratories ranged from 0.0004 to 0.08 μg/g, depending on the pesticide.